Methoxychlor as a Model for Environmental Estrogens
نویسندگان
چکیده
منابع مشابه
Universal assay of vitellogenin as a biomarker for environmental estrogens.
Vitellogenin (VTG), the serum phospholipoglycoprotein precursor to egg yolk, is potentially an ideal biomarker for environmental estrogens. This study was undertaken to develop antibodies against conserved regions on the VTG molecule that could form the basis for establishing bioassays to detect estrogen exposure in any oviparous vertebrate. We developed monoclonal antibodies (mAbs) generated a...
متن کاملEnvironmental Estrogens
John A. McLachlan and Steven F. Arnold n many ways, the story of the pesticide DDT is the story of America's attitude toward synthetic chemicals in the environment. DDT was the first of many new pesticides that people hoped would improve the quality of their lives, but gradually it became clear that such progress often had a cost. DDT was one of the first environmental chemical agents to*be ban...
متن کاملEnvironmental estrogens.
The estrogenic equivalent analysis that Dr. Safe presented recently in EHP (103:346-351) is a welcome addition to the literature , and development of this toxicologic approach is an important step in evaluating new endpoints for environmental agents (1,2). The hormonal potential of chemical contaminants offers many opportunities for further research, including study of the environmental etiolog...
متن کاملManure-borne estrogens as potential environmental contaminants: a review.
Livestock wastes are potential sources of endocrine disrupting compounds to the environment. Steroidal estrogen hormones such as estradiol, estrone, and estriol are a particular concern because there is evidence that low nanogram per liter concentrations of estrogens in water can adversely affect the reproductive biology of fish and other aquatic vertebrate species. We performed a literature re...
متن کاملPCBs as environmental estrogens: turtle sex determination as a biomarker of environmental contamination.
Polychlorinated biphenyls (PCBs) are widespread, low-level environmental pollutants associated with adverse health effects such as immune suppression and teratogenicity. There is increasing evidence that some PCB compounds are capable of disrupting reproductive and endocrine function in fish, birds, and mammals, including humans, particularly during development. Research on the mechanism throug...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Critical Reviews in Toxicology
سال: 1997
ISSN: 1040-8444,1547-6898
DOI: 10.3109/10408449709089899